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Explore our peer-reviewed publications advancing the science of microbiome diagnostics, personalized medicine, and therapeutic interventions.

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Immunology

Postbiotic Metabolites Modulate Immune Function and Reduce Systemic Inflammation in Elderly Populations

Costa A, Silva P, Martins L
Cell Host & Microbe
October 2025
53 citations

We investigated the immunomodulatory effects of specific postbiotic metabolites in a cohort of 200 elderly individuals. Our research demonstrated that targeted supplementation with bacterial-derived metabolites significantly reduced inflammatory markers (IL-6, TNF-α, CRP) and enhanced immune cell function. These findings support the therapeutic potential of postbiotics in age-related immune dysfunction and inflammaging.

DOI: 10.1016/j.chom.2023.09.012
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