Gastroenterology
Next-Generation Sequencing Reveals Novel Microbial Biomarkers for Early Detection of Inflammatory Bowel Disease
Silva P, Costa A, Rodrigues T, Santos M
Gastroenterology
November 2025
78 citations
This multi-center study utilized advanced NGS technology to analyze fecal microbiome samples from 500 individuals, including healthy controls and patients with various stages of inflammatory bowel disease. We identified a panel of 15 microbial biomarkers that demonstrated 92% sensitivity and 89% specificity for early IBD detection. These findings have significant implications for non-invasive screening and early intervention strategies.
DOI:
10.1053/j.gastro.2023.10.045
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