Diagnostic & Microbiome tests

The BioArte ISO 9001:2015 is an expert medical pathology testing, research, and development laboratory working with global medical, pharmaceutical, food, biotechnology, and clinical research organizations.

The laboratory provides a wide range of services in both diagnostic and microbiome research fields for both professionals and individuals.

The BioArte laboratory provides a range of services that includes:

  • Next-Generation Sequencing (NGS)
  • Polymerase Chain Reaction (PCR)
  • Immunoassay tests for Virology, Immunology & Biochemistry

Microbiota

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Advanced Gut Microbiota test kit
The BioArte gut test is the only test so far utilizing the BioArte proprietary 16s approach that can reach species level. To guarantee unmatched precision and specificity in identifying the microorganisms present in your gut, we sequence all nine variable regions (V1-V9), in contrast to others in the market who only sequence a limited percentage (mostly V3-V4). The kit includes 1 collection tube & a personalised diet recommendations and probiotic intake. For additional tests, a second tube/kit will be included.
Additional tests & services:
  • Inflammatory test includes the testing of:
    • Calprotectin - a substance that your body releases when there is inflammation in your intestine. It is a protein biomarker and high levels are associated with active inflammatory conditions.
    • Gut acidity - acidity can be tested in order to diagnose a medical condition. The pH of human faeces is variable but normally is alkaline.
  • Inflammation Marker Package: Fecal Zonulin & Secretory IgA provides a comprehensive assessment of gut permeability and immune function by measuring fecal Zonulin and Secretory IgA. This package is designed to support the evaluation of gastrointestinal health, immune response, and barrier integrity. Our Inflammation Marker Package includes the testing of:
    • Zonulin Intestinal Permeability Marker - Zonulin is a protein involved in the regulation of intestinal tight junctions. High levels of Zonulin are associated with increased intestinal permeability ("Leaky Gut Syndrome"), which can lead to gastrointestinal disturbances and systemic inflammation.
    • Secretory IgA (sIgA) Gut Immunity & Barrier Function - Immunoglobulin A (IgA) is a crucial antibody involved in the body's immune defense. In its secretory form, it is present in mucus and bodily secretions, including stool, and is the primary immunoglobulin in mucosal immunity. Secretory IgA serves as a biomarker for assessing gut immunity and intestinal barrier function. This test is valuable for: Evaluating immunological activity in the gastrointestinal tract Monitoring intestinal infections and gut inflammation Tracking treatment progress in inflammatory bowel diseases (e.g., Crohn’s disease, ulcerative colitis)
      • Elevated sIgA levels suggest an active immune response to an antigen or pathogen.
      • Decreased sIgA levels may indicate reduced mucosal immunity, a response to treatment, or a worsening condition.
  • Metagenomic Shotgun Screening by The BioArte: The BioArte’s metagenomic shotgun screening is the most advanced, untargeted tool for comprehensive analysis of the human microbiome and beyond. This technology allows full sequencing of all DNA extracted from biological samples, providing a complete genetic picture of all microorganisms present — without being limited to specific marker genes.
    • What it detects:
      • Bacteria: identified down to species and, in many cases, strain level.
      • Fungi: direct detection of fungal species without the need for culture.
      • Parasites: identification of intestinal parasites and protozoa.
      • Viruses: metagenomic detection of DNA viruses, including latent or low-abundance viral infections.
      • Antibiotic resistance genes: comprehensive mapping of key antibiotic resistance genes present in the sample’s microbial community.
    • Key advantages:
      • Unbiased approach: the method detects any organism present, including rare, unexpected, or emerging pathogens.
      • High resolution: allows for precise taxonomic classification and detection of genetic variants.
      • Identification of co-infections: the system detects mixed infections (bacterial, viral, fungal, parasitic) and determines the dominant pathogen.
      • Detection of emerging or unknown pathogens: ideal for research, precision medicine, and complex clinical cases.
    • Applications:
      1. Advanced diagnostics for immunocompromised patients.
      2. Monitoring hospital-acquired infections and multidrug-resistant organisms.
      3. Investigating intestinal dysbiosis.
      4. Environmental and food safety testing for microbial contamination.
      The BioArte’s standard of quality: All processes are carried out in The BioArte’s certified laboratory using state-of-the-art next-generation sequencing technologies (Oxford Nanopore), combined with proprietary bioinformatics pipelines designed to deliver the highest accuracy in taxonomic identification and antimicrobial resistance gene profiling. Each test is delivered with a detailed scientific report and the possibility of personalized scientific consultation.
  • Parasite test - This In Vitro Diagnostics (IVD) test is used as an aid in the diagnosis of Cryptosporidium, Giardia lamblia and/or Entamoeba histolytica in stool samples. DNA is extracted from stool specimens and analysed in our laboratory using Real Time PCR. These protozoan parasites are some of the most common intestinal parasites to cause gastrointestinal infections and are known as cryptosporidiosis, giardiasis and amoebiasis, respectively. Symptoms of the diseases include diarrhea, abdominal discomfort, bloating and weight loss.
  • Nutritional consultation - Book a consultation with our nutritionist who will be able to provide you with a plan of action based on your results.
250.00-700.00
Max:
Min: 1
Step: 1
Advanced Oral Microbiota test kit – Shotgun Nanopore Technology
Your mouth holds valuable insights into your overall health. Unlock them with our Advanced Oral Microbiota Test, powered by state-of-the-art sequencing technology. The oral cavity is home to a rich and dynamic microbial ecosystem, composed of over 700 species of bacteria, viruses, fungi, and protozoa. When balanced, this ecosystem plays a vital role in maintaining oral health by supporting immune defenses, regulating bioactive metabolites, preventing pathogenic overgrowth, and preserving tissue integrity. Your oral microbiome is closely linked not only to oral conditions, but also to immune function and systemic health. Our test uses high-resolution shotgun nanopore sequencing to deliver a comprehensive analysis of all microbial communities present in your mouth — far beyond traditional bacterial-only approaches. With this advanced profiling, you gain deep insights into your unique oral microbiome, including the detection of bacteria, fungi, viruses, and antibiotic resistance genes, helping you better understand your oral health and make informed, preventive choices.
260.00
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Min: 1
Step: 1
Advanced Vaginal Microbiome test – Shotgun Nanopore Technology
The female body tells a story of strength and balance. Discover yours with our Vaginal Microbiota Kit. Comprehensive insights into your intimate health with cutting-edge sequencing! Your vaginal microbiome is a complex ecosystem that influences everything from infection risk to fertility and antibiotic resistance. Our Vaginal Microbiome Test, powered by shotgun nanopore sequencing, provides an in-depth analysis of all microbial communities present, including bacteria, fungi, viruses, and antibiotic resistance genes. Take control of your intimate health today with the most advanced vaginal microbiome test available!
260.00
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Min: 1
Step: 1
Consultation with a Microbiota expert
This product is only available for customers who have purchased a kit and would like to book a consultation with our Microbiota expert.
150.00
Max:
Min: 1
Step: 1
Consultation with a Nutritionist
This product is only available for customers who have purchased a kit and would like to book a consultation with our Nutritionist.
75.00
Max:
Min: 1
Step: 1
Gut Microbiota – Test Package – Mother & Child/ren
The BioArte gut test is the only test so far utilizing the BioArte proprietary 16s approach that can reach species level. To guarantee unmatched precision and specificity in identifying the microorganisms present in your gut, we sequence all nine variable regions (V1-V9), in contrast to others in the market who only sequence a limited percentage (mostly V3-V4).
Package:
  • Mother and Child: This package allows you to perform a complete gut microbiota analysis for both mother and child at a discounted price compared to purchasing two individual tests.
  • Mother and Two Children: A dedicated package for families who want to professionally assess and improve their gut health.

Type of test:
  • Basic package: Gut microbiota test ONLY
  • Advanced package: Gut microbiota test +
    • Inflammatory test includes the testing of:
      • Calprotectin - a substance that your body releases when there is inflammation in your intestine. It is a protein biomarker and high levels are associated with active inflammatory conditions.
      • Gut acidity - acidity can be tested in order to diagnose a medical condition. The pH of human faeces is variable but normally is alkaline.
    • Inflammation Marker Package: Fecal Zonulin & Secretory IgA provides a comprehensive assessment of gut permeability and immune function by measuring fecal Zonulin and Secretory IgA. This package is designed to support the evaluation of gastrointestinal health, immune response, and barrier integrity. Our Inflammation Marker Package includes the testing of:
      • Zonulin Intestinal Permeability Marker - Zonulin is a protein involved in the regulation of intestinal tight junctions. High levels of Zonulin are associated with increased intestinal permeability ("Leaky Gut Syndrome"), which can lead to gastrointestinal disturbances and systemic inflammation.
      • Secretory IgA (sIgA) Gut Immunity & Barrier Function - Immunoglobulin A (IgA) is a crucial antibody involved in the body's immune defense. In its secretory form, it is present in mucus and bodily secretions, including stool, and is the primary immunoglobulin in mucosal immunity. Secretory IgA serves as a biomarker for assessing gut immunity and intestinal barrier function. This test is valuable for: Evaluating immunological activity in the gastrointestinal tract Monitoring intestinal infections and gut inflammation Tracking treatment progress in inflammatory bowel diseases (e.g., Crohn’s disease, ulcerative colitis)
        • Elevated sIgA levels suggest an active immune response to an antigen or pathogen.
        • Decreased sIgA levels may indicate reduced mucosal immunity, a response to treatment, or a worsening condition.
  • Enhanced package: Gut microbiota test + Shotgun Method (bacteria, fungi, viruses, parasites, several genes) +
    • Inflammatory test includes the testing of:
      • Calprotectin - a substance that your body releases when there is inflammation in your intestine. It is a protein biomarker and high levels are associated with active inflammatory conditions.
      • Gut acidity - acidity can be tested in order to diagnose a medical condition. The pH of human faeces is variable but normally is alkaline.
    • Inflammation Marker Package: Fecal Zonulin & Secretory IgA provides a comprehensive assessment of gut permeability and immune function by measuring fecal Zonulin and Secretory IgA. This package is designed to support the evaluation of gastrointestinal health, immune response, and barrier integrity. Our Inflammation Marker Package includes the testing of:
      • Zonulin Intestinal Permeability Marker - Zonulin is a protein involved in the regulation of intestinal tight junctions. High levels of Zonulin are associated with increased intestinal permeability ("Leaky Gut Syndrome"), which can lead to gastrointestinal disturbances and systemic inflammation.
      • Secretory IgA (sIgA) Gut Immunity & Barrier Function - Immunoglobulin A (IgA) is a crucial antibody involved in the body's immune defense. In its secretory form, it is present in mucus and bodily secretions, including stool, and is the primary immunoglobulin in mucosal immunity. Secretory IgA serves as a biomarker for assessing gut immunity and intestinal barrier function. This test is valuable for: Evaluating immunological activity in the gastrointestinal tract Monitoring intestinal infections and gut inflammation Tracking treatment progress in inflammatory bowel diseases (e.g., Crohn’s disease, ulcerative colitis)
        • Elevated sIgA levels suggest an active immune response to an antigen or pathogen.
        • Decreased sIgA levels may indicate reduced mucosal immunity, a response to treatment, or a worsening condition.
400.00-1,000.00
Max:
Min: 1
Step: 1

Immunology

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Food Intolerance test
Many people exhibit chronic food sensitivity reactions to specific foods. The reaction towards a given food group might be exhibited as an immunological reaction by an increase in either IgG and/or IgE antibodies. Unlike the immediate effects of IgE-mediated allergy, IgG-mediated food sensitivity reactions may take several days to appear. Food intolerance* refers to gastrointestinal (GI) discomfort due to IgG antibodies which are sensitized by specific food proteins. Irritable bowel syndrome may also be linked to food sensitivity (IgG). The test will quantify the titer of IgG antibodies which are found against 220 different foods including: soya, beans, yeast, legumes, vegetables, egg, grains, seafood, meat, milk, weed pollen, spices, nuts, seeds, berries, fruits, fish, and others (including mushrooms, cacao, gelatin, coffee, etc.) * The food intolerance tests are not the same as the food allergy test, lactose intolerance, or coeliac tests. We also recognize that the link between raised food-specific IgG levels and specific symptoms is not well understood in the medical community.
150.00
Max:
Min: 1
Step: 1

Genetics

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Carrier Screening test
Carrier screening is a comprehensive test that helps individuals understand their risk of passing on genetic conditions to their children. Using advanced Next Generation Sequencing (NGS) with high detection rates for common and rare conditions, this test screens for up to 231 genes covering a wide range of autosomal recessive and X-linked disorders.
230.00-810.00
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Min: 1
Step: 1
HLA test for Celiac disease
At the molecular level, celiac disease is induced by an immune reaction to gluten, a protein found in wheat, barley, and rye. Celiac disease has a strong hereditary component. The HLA test for celiac disease is a test that assesses an individual's genetic predisposition to develop the disease. Human leukocyte antigen (HLA) is used to confirm or exclude the possibility of celiac disease. The DNA test allows effectively to rule out (99%) the disease if no HLA-DQ2/DQ8 risk types are detected. This allows for avoiding the disease and all the consequences associated with it. If the result is negative, it is unlikely that you will develop the disease. If the result is positive, you can follow up with your healthcare provider for further evaluation. Diagnostic detection of main HLA alleles associated with celiac disease by VIASURE HLA Celiac Real-Time PCR Detection Kit.
150.00
Max:
Min: 1
Step: 1
Infertility Genetic test Couple panel
Infertility Genetic Test offers genetic insights for individuals or couples facing infertility. By screening for chromosomal and single-gene causes, this test can uncover the underlying genetic factors contributing to fertility challenges, recurrent pregnancy loss, or thrombophilia.
765.00-1,365.00
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Min: 1
Step: 1
Infertility Genetic test Single panel
Infertility Genetic Test offers genetic insights for individuals or couples facing infertility. By screening for chromosomal and single-gene causes, this test can uncover the underlying genetic factors contributing to fertility challenges, recurrent pregnancy loss, or thrombophilia.
510.00-810.00
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Min: 1
Step: 1
Nutrigenomics test
A predictive DNA test that serves as a compass allowing you to identify areas of strength and weakness that guide you in choosing conscious behavior for a healthy life. The test identifies the presence of genetic variants that may be associated with a predisposition to develop a certain pathology. This test provides information on the following:
  • Metabolic: regulation of hunger and food metabolism
  • Intolerances & Allergies: predisposition to allergies and intolerances
  • Micronutrients: deficiency of vitamins and mineral salts
  • Inflammatory: response to inflammatory stimuli
  • Additional test: Pharmacogenomics: drug metabolism
550.00-650.00
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Min: 1
Step: 1
STD Screening test
This test is only available in Malta. Sexually Transmitted Diseases Real-Time PCR Detection Kit is designed for the specific identification and differentiation of Neisseria gonorrhoeae (causative agent for Gonorrhea), Chlamydia trachomatis (causative agent for Chlamydia), Mycoplasma genitalium (causative agent for Pelvic Inflammatory Disease), Trichomonas vaginalis (causative agent for Trichomoniasis), Ureaplasma urealyticum (causative agent for Pelvic Inflammatory Disease), Ureaplasma parvum and/or Mycoplasma hominis (associated with Infertility and Pelvic Inflammatory Disease) Analysis is done on samples taken from urogenital, endocervical and urine, from patients with signs and symptoms of sexually transmitted diseases (STDs). This test is intended for use as an aid in the diagnosis of STDs in combination with clinical and epidemiological risk factors. DNA is extracted from clinical specimens, multiplied using Real-Time amplification, and detected using fluorescent reporter dye probes specific for:
  • Trichomonas vaginalis (Causative organism for vaginal/urethral infection)
  • Mycoplasma hominis (Causative organism for genital inflammation in women)
  • Mycoplasma genitalium (Causative organism for genital inflammation in men)
  • Ureaplasma spp. (Causes inflammation)
  • Neisseria gonorrhoeae (Causative organism for Gonorrhea)
  • Chlamydia trachomatis (Causative organism for Chlamydia)
99.00-170.00
Max:
Min: 1
Step: 1
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