Inflammation Marker Package: Faecal Zonulin & Secretory IgA
Enzyme-linked immunosorbent assay (ELISA)
A stool-based inflammation marker package that assesses intestinal permeability and mucosal immune activity by measuring faecal zonulin and secretory IgA, helping support evaluation of gut barrier integrity, immune response, and gastrointestinal health.
What's Included
Full Description
This package provides a combined assessment of gut permeability and mucosal immune function by measuring zonulin and secretory IgA in stool (faeces). Zonulin is involved in the regulation of intestinal tight junctions, and increased levels are associated with increased intestinal permeability, commonly referred to as “leaky gut”. Secretory IgA is the primary immunoglobulin found in mucosal secretions, including stool, and supports intestinal immune defence and barrier function.
The test may be useful for evaluating immunological activity in the gastrointestinal tract, monitoring intestinal infections or gut inflammation, and tracking treatment progress in inflammatory bowel diseases such as Crohn’s disease and ulcerative colitis. Elevated secretory IgA may suggest an active mucosal immune response, while decreased levels may indicate reduced mucosal immunity, response to treatment, or worsening barrier-related status. Results should be interpreted together with symptoms, medical history, and other relevant investigations.
The Process: from purchase to results
- Order your test – The kit is delivered to your door. Once you purchase your test kit, you will receive an email with a link to the Customer Guide. You will need to log in (using the credentials you created upon purchasing the kit), to access the Customer guide.
- Fill in the form – Submit the online consent form, medical history questionnaire, and sample collection date/s.
- Collect your samples – Follow the step-by-step instructions for stool sample collection.
- Send it back – Return your sample using the mailing bag with prepaid return shipping label.
- Receive your report – Get your faecal zonulin and secretory IgA results within 4-5 weeks of sample receipt.
Optional Add-Ons/Related Tests
Intestinal Inflammation & Stool Acidity
Gut Microbiome Testing
Stool Parasite Testing
Nutritional Consultation
Key Features
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Measures faecal zonulin, a marker linked to intestinal tight junction regulation and gut permeability.
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Measures secretory IgA, the main immunoglobulin involved in mucosal immune defence and intestinal barrier function.
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Supports assessment of gastrointestinal immune activity, gut inflammation, and treatment monitoring when interpreted with clinical context.
Frequently Asked Questions
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What complementary tests or services should I consider?
Calprotectin & Faecal pH
Testing for intestinal inflammation and stool acidity.
Gut Microbiota Testing
Comprehensive assessment of gut microorganisms together with personalised dietary recommendations.
Parasite Testing
Real‑time PCR detection of common intestinal parasites (Cryptosporidium, Giardia lamblia and/or Entamoeba histolytica)
